Nightlife prevention in the city of Zurich is part of the Social Department - Youth Counselling Streetwork. The objective is to promote a healthier nightlife. The intervention is based on drug-checking with counselling (on site and local), an alcohol intervention on site and in public spaces, and collaboration with the different stakeholders. Drug-checking, in combination with a counselling session, is an effective method of reaching the target group of party drug consumers. Drug-checking gives higher credibility to prevention messages. If drug-checking is linked with therapeutic services it can be helpful to triage people to this service.